“Eva, es una persona con elevada calidad humana, la cercanía que me ofreció desde el día que la conocí me facilita hablar de su integridad como persona. Tiene elevada capacidad de escucha, comprensión y cortesía para ayudar a solucionar problemas. Además, es una persona que se involucra con el bienestar de su entorno, lo cual permite un agradable ambiente de trabajo. Desde el año 2010 ví cómo enfrentó diferentes retos de la investigación, soy testigo de su gran labor y paciencia en los proyectos de neurofisiología del sueño-vigilia con EEG ya que trabajamos durante 2 años en el mismo laboratorio. Además, he visto su elevada implicación y compromiso en el desarrollo de artículos científicos en revistas de elevado impacto, así como de sus capacidades de liderazgo y motivación para desarrollar proyectos de investigación. Recomiendo a Eva en el campo de la investigación y docencia. Es una persona con elevado potencial de cooperación y empatía para desarrollar ideas que le sean planteadas, que sumado a su paciencia y perseverancia hacen un perfil profesional deseable en cualquier proyecto de investigación.”
Eva Hita Yáñez, PhD
Directora del Departamento de Recursos Humanos en CFI Reina Isabel
Greater Granada Metropolitan Area
721 followers
500+ connections
About
Licenciada en Psicología por la Universidad de Granada en julio de 2007, realicé el Máster en Diseños de Investigación y aplicaciones en Psicología y Salud de la Universidad de Granada. El 17 de enero de 2014 obtuve el doctorado en Neurociencias por la Universidad Pablo de Olavide con calificación de sobresaliente cum laude. En 2017 finalice el Master en Gestión y Dirección de Recursos Humanos y Coaching de la Cámara de Comercio de Granada.
He formado parte como investigadora a cargo de diferentes proyectos de investigación. Durante esta trayectoria he publicado varios artículos científicos, todos ellos indexados en el Journal Citation Reports (JCR), así como capítulos de libros. He participado en docencia universitaria (cursos de grado y posgrado), dirigido una Tesis Doctoral y, actualmente, colaboro como directora de Trabajos Fin de Máster con la Universidad Internacional de Valencia. Además, he gestionado el desarrollo de diferentes Proyectos de Investigación, uno de ellos financiado por Grupo Lo Monaco S.L.
Activity
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https://lnkd.in/dj_4592M Proyecto europeo sobre Estrés Perinatal
https://lnkd.in/dj_4592M Proyecto europeo sobre Estrés Perinatal
Liked by Eva Hita Yáñez, PhD
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Llega el momento más emotivo del Acto de Investidura como Doctor Honoris Causa al periodista Vicente Vallés. Nuestra Rectora, Eva Mª Giner Larza le…
Llega el momento más emotivo del Acto de Investidura como Doctor Honoris Causa al periodista Vicente Vallés. Nuestra Rectora, Eva Mª Giner Larza le…
Liked by Eva Hita Yáñez, PhD
Experience
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VIU - Universidad Internacional de Valencia
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CFI Reina Isabel
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Universidad de Granada
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Responsable Laboratorio de sueño . Proyecto colaboración UGR - Grupo LO MONACO
Centro de Investigacion Mente, Cerebro y Comportamiento (CIMCYC). Universidad de Granada
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Universidad Pablo de Olavide
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Monitor residencial
FAISEM
Education
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Cámara de comercio de Granada
Máster Dirección y Gestión RRHH y Coaching Recursos Humanos y coaching
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Universidad Pablo de Olavide
Doctora en Neurociencias Programa Oficial de Posgrado en Neurociencias Sobresaliente cum laude
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Caracterización de las alteraciones del sueño en personas mayores con deterioro cognitivo leve
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Universidad de Granada
Master en diseños de investigación y aplicaciones en psicología y salud PSYCHOLOGY
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Licenses & Certifications
Volunteer Experience
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Educadora infantil
Escuela Hogar Divina Infantita
- 9 months
Children
Publications
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Que es el sueño
TERAPIA COGNITIVOCOMPORTAMENTAL PARA TRANSTORNOS DO SONO/CRV
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Sleep Characteristics in Children with Attention Deficit Hyperactivity Disorder: Systematic Review and Meta-Analyses.
Journal of Clinical Sleep Medicine.
STUDY OBJECTIVES:
Sleep disturbances have been associated with attention deficit hyperactivity disorder (ADHD), but such relationship is still unclear. The results from the studies conducted do not provide enough evidence to support a sleep physiology inherent to ADHD. This study tries to determine if that sleep physiology really exists by comparing children with ADHD and control children in some sleep parameters.
METHODS:
A search was conducted in several databases (Web…STUDY OBJECTIVES:
Sleep disturbances have been associated with attention deficit hyperactivity disorder (ADHD), but such relationship is still unclear. The results from the studies conducted do not provide enough evidence to support a sleep physiology inherent to ADHD. This study tries to determine if that sleep physiology really exists by comparing children with ADHD and control children in some sleep parameters.
METHODS:
A search was conducted in several databases (Web of Science, Scopus, Pubmed and PsycINFO), and a manual search, to retrieve all the articles available from 1987 until March 2014. Of 8,678 non-duplicate studies retrieved, 11 studies met the inclusion and methodological quality criteria. Two meta-analyses were performed with eight of those studies, depending on data provided by them: polysomnographic or actigraphic. A fixed-effects model, and the standardized mean difference (SMD) as the index of effect size, were used in both meta-analyses.
RESULTS:
Significant differences were found only in the meta-analysis with polysomnography as outcome. Children with ADHD were found to spend more time in stage 1 sleep than controls (pooled SMD = 0.32, 95% CI = 0.08-0.55, p value = 0.009).
CONCLUSIONS:
Although few differences in sleep between children with ADHD and controls have been found in this review, further studies are required on this matter. Those studies should consider some variables discussed in this review, in order to obtain useful and reliable conclusions for research and clinical practice. Particularly, the influence of assessment criteria and ADHD subtypes in the sleep characteristics of children with ADHD should be addressed
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Polysomnographic and subjective sleep markers of mild cognitive impairment.
Sleep
STUDY OBJECTIVES:
Growing evidence suggests that sleep disturbances precede by years the clinical onset of Alzheimer disease (AD). The goal of the current study is to determine whether changes in polysomnographic (PSG) sleep patterns accompany subjective sleep complaints in patients with mild cognitive impairment (MCI). We further examine whether meaningful changes in objective sleep physiology are predicted by self-reported sleep measures in MCI patients, and whether incipient…STUDY OBJECTIVES:
Growing evidence suggests that sleep disturbances precede by years the clinical onset of Alzheimer disease (AD). The goal of the current study is to determine whether changes in polysomnographic (PSG) sleep patterns accompany subjective sleep complaints in patients with mild cognitive impairment (MCI). We further examine whether meaningful changes in objective sleep physiology are predicted by self-reported sleep measures in MCI patients, and whether incipient neurodegeneration contributes to exacerbate sleep misperception.
DESIGN SETTING AND PARTICIPANTS:
Overnight PSG recordings and self-reported sleep measures were obtained from 25 healthy elderly (HE) subjects and 25 patients with MCI at the sleep laboratory.
RESULTS:
Both PSG and self-reported sleep measures confirmed that sleep is altered in patients with MCI. Whereas subjective sleep responses predicted fragmentation of slow wave sleep (SWS) in HE individuals, this relationship was not evident in MCI patients. Furthermore, patients with MCI showed significant discrepancies in the estimation of sleep onset latency when compared with HE subjects.
CONCLUSIONS:
Sleep is significantly impaired in patients with mild cognitive impairment at both the objective and subjective level, which may be used as a surrogate marker of preclinical Alzheimer disease. Taken together, these findings aid in the development of novel therapeutic strategies devoted to improve sleep in the elderly population at risk of developing Alzheimer disease.
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Disturbed sleep patterns in elders with mild cognitive impairment: The role of memory decline and ApoE ε4 genotype.
Current Alzheimer Research
Sleep disturbances are prevalent in patients with Alzheimer' disease (AD), being one of the most troubling symptoms during the progression of disease. However, little research has been made to determine if impaired sleep patterns appear years before AD diagnosis. This study tries to shed light on this issue by performing polysomnographic recordings in healthy elders and patients with mild cognitive impairment (MCI). We further investigated whether changes in sleep patterns parallel memory…
Sleep disturbances are prevalent in patients with Alzheimer' disease (AD), being one of the most troubling symptoms during the progression of disease. However, little research has been made to determine if impaired sleep patterns appear years before AD diagnosis. This study tries to shed light on this issue by performing polysomnographic recordings in healthy elders and patients with mild cognitive impairment (MCI). We further investigated whether changes in sleep patterns parallel memory decline as well as its relationship with the Apolipoprotein E (ApoE) ɛ4 genotype. Results showed a significant shortening of rapid eye movement (REM) sleep together with increased fragmentations of slow-wave sleep in MCI patients relative to healthy elders. Interestingly, we further showed that reduction of REM sleep in MCI patients with ApoE ɛ4 was more noticeable than in ɛ4 non-carriers. Contrary to our initial hypothesis, changes in sleep patterns were not correlated with memory performance in MCI patients. Instead, increased REM sleep accompanied enhanced immediate recall in MCI ɛ4 non-carriers. Taken together, these results suggest that sleep disruptions are evident years before diagnosis of AD, which may have implications for early detection of dementia and/or therapeutic management of sleep complaints in MCI patients.
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Factores asociados a la calidad de sueño en adultos sin problemas de sueño: medidas subjetivas y objetivas.
En Quevedo-Blasco, R y Quevedo Blasco, J. V. (Eds.), Avances en Psicología Clínica (pp. 827-830). España, Granada: AEPC. Ref.: ISBN: 978-84-695-3599-8
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Progressive reduction of sleep time and quality in rats with hepatic encephalopathy due to portacaval shunts.
Neuroscience
Patients with liver cirrhosis show sleep disturbances. Insight into their relationship with hepatic encephalopathy (HE) can be obtained using animal models of HE. The aims of this work were to assess (1) whether rats with portacaval shunts (PCS), a model of HE, show alterations in sleep and if they are similar to those in patients with HE; (2) Whether hyperammonemia plays a role in these sleep alterations; and (3) the time course of sleep alterations in these animal models. Rats were subjected…
Patients with liver cirrhosis show sleep disturbances. Insight into their relationship with hepatic encephalopathy (HE) can be obtained using animal models of HE. The aims of this work were to assess (1) whether rats with portacaval shunts (PCS), a model of HE, show alterations in sleep and if they are similar to those in patients with HE; (2) Whether hyperammonemia plays a role in these sleep alterations; and (3) the time course of sleep alterations in these animal models. Rats were subjected to PCS to induce HE. Another group of rats was fed an ammonium-containing diet to induce hyperammonemia. Polysomnographic recordings were acquired for 24 h and sleep architecture was analyzed in control, PCS, and hyperammonemic rats at 4, 7, and 11 weeks after surgery or diet, respectively. PCS rats show a significant reduction in rapid eye movement (REM) and non-rapid eye movement (NREM) sleep time and increased sleep fragmentation, whereas reduced sleep occurs at 4 weeks and worsens at 7 and 11 weeks, sleep fragmentation appears at 7 weeks and worsens at 11 weeks. Hyperammonemic rats show decreased REM sleep, starting at 7 weeks and worsening at 11 weeks, with no changes in NREM sleep or sleep fragmentation. Therefore, PCS rats are a good model to study sleep alterations in HE, their mechanisms, and potential treatment. Mild hyperammonemia mainly impacts mechanisms involved in REM generation and/or maintenance but does not seem to be involved in sleep fragmentation.
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Sleep and Mild Cognitive Impairment
En McNamara, P., Barrett, D. (Eds.), Encyclopedia of Sleep and Dreams: The Evolution, Function, Nature, and Mysteries of Slumber (pp. 619-620). Santa Bárbara, California: ABC-CLIO.
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Tau Protein and Sleep–Wake Cycle
En McNamara, P., Barrett, D. (Eds.), Encyclopedia of Sleep and Dreams: The Evolution, Function, Nature, and Mysteries of Slumber (pp. 760-761). Santa Bárbara, California: ABC-CLIO.
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Attentional deficits in fibromyalgia and its relationships with pain, emotional distress and sleep dysfunction complaints.
Psychology and Health
Cognitive complaints are common among subjects with fibromyalgia (FM). Yet, few studies have been able to document these deficits with cognitive tasks. A main limitation of existing studies is that attention has been broadly defined and the tasks used to measure attention are not designed to cover all the main components of the attentional system. Research on attention has identified three primary functions of attention, known as alerting, orienting and executive functioning. This study used…
Cognitive complaints are common among subjects with fibromyalgia (FM). Yet, few studies have been able to document these deficits with cognitive tasks. A main limitation of existing studies is that attention has been broadly defined and the tasks used to measure attention are not designed to cover all the main components of the attentional system. Research on attention has identified three primary functions of attention, known as alerting, orienting and executive functioning. This study used the attentional network test-interactions task to explore whether and which of the three attentional networks are altered in FM. Results showed that FM patients have impaired executive control (greater interference), reduced vigilance (slower overall reaction time) and greater alertness (higher reduction in errors after a warning cue). Vigilance and alertness showed several relations with depression, anxiety and sleep quality. Sleep dysfunction was a significant predictor for alertness, whereas there were no significant predictors for vigilance. These findings highlight that the treatment of sleep difficulties in FM patients may help with some of their cognitive complaints.
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Role of tau protein on neocortical and hippocampal oscillatory patterns.
Hippocampus
Tau is a neuronal microtubule-associated protein implicated in microtubules stabilization, axonal establishment and elongation during neuronal morphogenesis. Because of its elevated expression in neocortical regions and hippocampus, tau might play a role in sculpting collective neural responses underlying slow and fast brain oscillations and/or long-range synchronization patterns between hippocampus and neocortex. To test this hypothesis, local field potentials were recorded in tau-deficient…
Tau is a neuronal microtubule-associated protein implicated in microtubules stabilization, axonal establishment and elongation during neuronal morphogenesis. Because of its elevated expression in neocortical regions and hippocampus, tau might play a role in sculpting collective neural responses underlying slow and fast brain oscillations and/or long-range synchronization patterns between hippocampus and neocortex. To test this hypothesis, local field potentials were recorded in tau-deficient (tau(-/-) ) and wild-type mice from different neocortical regions and from the hippocampus during spontaneous motor exploratory behavior. We found that tau(-/-) mice showed hippocampal theta slowing and reduced levels of gamma long-range synchronization involving the frontal cortex. We hypothesize that the lack of normal phosphorylated tau during early stages of development might influence the maturation of parvalbumin interneurons affecting the spatiotemporal structure of long-range gamma synchronization. Also, the proper functioning of gap-junction channels might be compromised by the absence of tau in hippocampal networks. Altogether, these results provide novel insights into the functional role of tau protein in the formation of collective neural responses and emergence of neocortical-hippocampal interactions in the mammalian brain.
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Tau protein role in sleep-wake cycle
Journal of Alzheimer’s Disease
Evidence has shown that the lack of tau produces subtle changes in neuronal structure and modest impairment in complex behaviors, suggesting compensatory mechanisms carried out by other neuronal microtubule-associated proteins. Here we show major abnormalities in sleep-wake cycle of tau-deficient animals including increased wakefulness duration and decreased non-rapid eye movement (NREM) sleep time, a higher number of state transitions between NREM and wake, and shortened sleep bouts. Altered…
Evidence has shown that the lack of tau produces subtle changes in neuronal structure and modest impairment in complex behaviors, suggesting compensatory mechanisms carried out by other neuronal microtubule-associated proteins. Here we show major abnormalities in sleep-wake cycle of tau-deficient animals including increased wakefulness duration and decreased non-rapid eye movement (NREM) sleep time, a higher number of state transitions between NREM and wake, and shortened sleep bouts. Altered sleep structure in tau-/- mice was accompanied by a significant decline in delta power together with an enhanced spectral density of sleep spindles during NREM sleep. No significant differences were observed in rapid eye movement (REM) sleep between the two mouse strains. Taken together, these results suggest that tau indirectly participates in the regulation of the sleep-wake cycle modulating not only the control and maintenance of global brain states but also the cerebral oscillatory patterns underlying sleep-wake states.
Other authors
Projects
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Impacto del sueño sobre el rendimiento escolar y cognitivo en niños con trastorno por déficit de atención e hiperactividad financiado por el Ministerio de Economía y Competitividad en el Programa de excelencia (PSI2014-58046-P)
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Análisis de la calidad del sueño y del rendimiento cognitivo en impulsividad e hiperactividad en niños financiado Ministerio de Economía y Competitividad en el Programa Retos (EDU 2010-21215)
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Influencia del equipo de descanso en la calidad del sueño y en la actividad diaria en personas con dolor de espalda financiado a través de un Convenio de mecenazgo entre Grupo Lo Monaco S.L. y la Universidad de Granada.
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Languages
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Español
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Ingles
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¡Grandes noticias desde CFI Reina Isabel! Nos enorgullece anunciar que, por segunda vez, hemos sido invitados como socios en un importante proyecto…
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